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Cardiff Oncology, Inc. (CRDF) Fundamental Analysis & AI Grade 2026

CRDF Nasdaq Biological Products, (No Diagnostic Substances) DE CIK: 0001213037
Updated This Month • Analysis: May 16, 2026 • SEC Data: 2026-03-31
Combined AI Grade
D
88% Confidence
STRONG AGREEMENT
D
85% Conf
D
90% Conf

📊 CRDF Key Takeaways

Revenue: $41.0K
Net Margin: -30,109.8%
Free Cash Flow: $-12.3M
Current Ratio: 3.27x
Debt/Equity: 0.00x
EPS: $-0.18
AI Grade: D with 85% confidence
Cardiff Oncology, Inc. (CRDF) receives a D fundamental grade with 88% confidence from our AI analysis based on SEC 10-K filings. With revenue of $41.0K, net profit margin of -30,109.8%, and return on equity (ROE) of -35.6%, Cardiff Oncology, Inc. demonstrates mixed fundamentals in the Healthcare sector. Below is our complete CRDF stock analysis for 2026.

Is Cardiff Oncology, Inc. (CRDF) a Good Investment?

Claude

Cardiff Oncology is a pre-revenue biotech company with virtually no commercial traction ($41K quarterly revenue) and severe cash burn ($12.3M annually) against a limited cash position of $8.5M, implying less than 1 year of runway at current burn rate. Despite a debt-free balance sheet and strong liquidity ratios, the company faces imminent funding requirements or operational restructuring, creating significant dilution risk to shareholders.

ChatGPT

Cardiff Oncology’s fundamentals remain very weak: revenue is minimal and declining, while operating and free cash flow losses are extremely large relative to its asset and equity base. The balance sheet has no long-term debt and acceptable near-term liquidity, but the current cash position appears insufficient against the company’s annual cash burn, making future dilution or external financing a central risk.

Cardiff Oncology, Inc. Key Strengths (CRDF)

Claude
  • + Zero long-term debt and no leverage provides balance sheet flexibility
  • + Strong liquidity position with 3.27x current/quick ratios provides near-term operational cushion
  • + Positive stockholders' equity of $34.7M provides shareholder protection relative to liabilities
  • + Minimal capital expenditure requirements suggest asset-light development model
ChatGPT
  • + Debt-free balance sheet with no long-term debt
  • + Current and quick ratios of 3.67x support near-term obligations
  • + Net loss was roughly flat year over year and diluted EPS improved year over year

CRDF Stock Risks: Cardiff Oncology, Inc. Investment Risks

Claude
  • ! Critically low cash runway of approximately 8 months at current $12.3M annual operating burn rate
  • ! Virtually non-existent revenue generation ($41K annually) indicates zero commercial viability
  • ! Declining revenue trajectory (-13.2% YoY) suggests worsening commercial position
  • ! Imminent capital raise needed will likely result in significant shareholder dilution
  • ! Binary outcome inherent to preclinical/clinical stage biotech with no validated pipeline asset generating revenue
  • ! Operating losses of $12.3M against minimal asset base unsustainable without external funding
ChatGPT
  • ! Operating income of -$48.96M and free cash flow of -$37.97M indicate an unsustainable business model without new funding
  • ! Cash and equivalents of $17.47M are low relative to operating cash burn of $37.92M
  • ! Revenue fell 13.2% year over year and remains too small to support operations

Key Metrics to Watch

Claude
  • * Cash runway and quarterly burn rate trends
  • * Pipeline milestone achievement and clinical trial progress
  • * Capital raise activity and terms (dilution percentage)
  • * Revenue inflection and partnership/licensing deals
ChatGPT
  • * Cash runway relative to quarterly operating cash burn
  • * Progress in revenue generation and reduction in operating loss

Cardiff Oncology, Inc. (CRDF) Financial Metrics & Key Ratios

Revenue
$41.0K
Net Income
$-12.3M
EPS (Diluted)
$-0.18
Free Cash Flow
$-12.3M
Total Assets
$49.2M
Cash Position
$8.5M

💡 AI Analyst Insight

Strong liquidity with a 3.27x current ratio provides a solid financial cushion.

CRDF Profit Margin, ROE & Profitability Analysis

Gross Margin N/A
Operating Margin -31,341.5%
Net Margin -30,109.8%
ROE -35.6%
ROA -25.1%
FCF Margin -30,078.0%

CRDF vs Healthcare Sector: How Cardiff Oncology, Inc. Compares

How Cardiff Oncology, Inc. compares to Healthcare sector averages

Net Margin
CRDF -30,109.8%
vs
Sector Avg 12.0%
CRDF Sector
ROE
CRDF -35.6%
vs
Sector Avg 15.0%
CRDF Sector
Current Ratio
CRDF 3.3x
vs
Sector Avg 2.0x
CRDF Sector
Debt/Equity
CRDF 0.0x
vs
Sector Avg 0.6x
CRDF Sector

Sector benchmarks are approximate industry averages. Actual sector performance may vary.

Is Cardiff Oncology, Inc. Stock Overvalued? CRDF Valuation Analysis 2026

Based on fundamental analysis, Cardiff Oncology, Inc. has mixed fundamental signals relative to the Healthcare sector in 2026.

Return on Equity
-35.6%
Sector avg: 15%
Net Profit Margin
-30,109.8%
Sector avg: 12%
Revenue Growth
N/A
Year-over-year
Debt/Equity
0.00x
Sector avg: 0.6x

Note: This is a fundamental analysis based on SEC filings. For P/E ratio, price targets, and market-based valuation, consult financial data providers. This is not investment advice.

Cardiff Oncology, Inc. Balance Sheet: CRDF Debt, Cash & Liquidity

Current Ratio
3.27x
Quick Ratio
3.27x
Debt/Equity
0.00x
Debt/Assets
29.4%
Interest Coverage
N/A
Long-term Debt
$0.0

CRDF Revenue & Earnings Growth: 5-Year Financial Trend

CRDF 5-year financial data: Year 2021: Revenue $366.0K, Net Income -$19.3M, EPS $-1.08. Year 2022: Revenue $386.0K, Net Income -$28.3M, EPS $-0.73. Year 2023: Revenue $488.0K, Net Income -$38.7M, EPS $-0.89. Year 2024: Revenue $683.0K, Net Income -$41.4M, EPS $-0.93. Year 2025: Revenue $683.0K, Net Income -$45.4M, EPS $-0.95.
Revenue
Net Income
EPS (right axis)

5-Year Trend Summary: Cardiff Oncology, Inc.'s revenue has grown significantly by 87% over the 5-year period, indicating strong business expansion. The most recent EPS of $-0.95 indicates the company is currently unprofitable.

CRDF Revenue Growth, EPS Growth & YoY Performance

Revenue Growth
N/A
Year-over-year
Net Income Growth
N/A
Year-over-year
EPS Growth
N/A
Earnings per share
FCF Margin
-30,078.0%
Free cash flow / Revenue

CRDF Quarterly Earnings & Performance

Quarterly financial performance data for Cardiff Oncology, Inc. including revenue, net income, and earnings per share.
Quarter Revenue Net Income EPS
Q1 2026 $41.0K -$12.3M $-0.18
Q3 2025 $120.0K -$10.0M $-0.17
Q2 2025 $121.0K -$10.0M $-0.21
Q1 2025 $109.0K -$10.0M $-0.20
Q3 2024 $141.0K -$9.7M $-0.22
Q2 2024 $108.0K -$10.0M $-0.25
Q1 2024 $83.0K -$10.0M $-0.22
Q3 2023 $93.0K -$8.6M $-0.20

Data sourced from SEC EDGAR 10-Q quarterly filings. Figures may represent quarterly or cumulative values.

Cardiff Oncology, Inc. Dividends, Buybacks & Capital Allocation

Operating Cash Flow
-$12.3M
Cash generated from operations
Stock Buybacks
$500.0K
Shares repurchased (TTM)
Capital Expenditures
$44.0K
Investment in assets
Dividends
None
No dividend program

CRDF SEC Filings: Latest 10-K & 10-Q Analysis

Access official SEC EDGAR filings for Cardiff Oncology, Inc. (CIK: 0001213037)

📋 Recent SEC Filings

Date Form Document Action
Jun 3, 2026 8-K crdf-20260603.htm View →
May 29, 2026 8-K crdf-20260527.htm View →
May 19, 2026 8-K crdf-20260519.htm View →
May 14, 2026 8-K crdf-20260514.htm View →
May 14, 2026 10-Q crdf-20260331.htm View →

Frequently Asked Questions about CRDF

What is the AI rating for CRDF?

Cardiff Oncology, Inc. (CRDF) has a Combined AI Grade of D from Claude (D) and ChatGPT (D) with 88% combined confidence, based on fundamental analysis of SEC EDGAR filings.

What are CRDF's key strengths?

Claude: Zero long-term debt and no leverage provides balance sheet flexibility. Strong liquidity position with 3.27x current/quick ratios provides near-term operational cushion. ChatGPT: Debt-free balance sheet with no long-term debt. Current and quick ratios of 3.67x support near-term obligations.

What are the risks of investing in CRDF?

Claude: Critically low cash runway of approximately 8 months at current $12.3M annual operating burn rate. Virtually non-existent revenue generation ($41K annually) indicates zero commercial viability. ChatGPT: Operating income of -$48.96M and free cash flow of -$37.97M indicate an unsustainable business model without new funding. Cash and equivalents of $17.47M are low relative to operating cash burn of $37.92M.

What is CRDF's revenue and growth?

Cardiff Oncology, Inc. reported revenue of $41.0K.

Does CRDF pay dividends?

Cardiff Oncology, Inc. does not currently pay dividends.

Where can I find CRDF SEC filings?

Official SEC filings for Cardiff Oncology, Inc. (CIK: 0001213037) including 10-K, 10-Q, and 8-K reports are available on SEC EDGAR.

What is CRDF's EPS?

Cardiff Oncology, Inc. has a diluted EPS of $-0.18.

How is the AI analysis conducted?

Two independent AI systems — Claude (Anthropic) and ChatGPT (OpenAI) — analyze SEC EDGAR filings including 10-K annual reports and 10-Q quarterly reports. Each AI evaluates financial health, profitability ratios, balance sheet strength, and growth metrics. The combined grade reflects both perspectives for balanced insights.

What is CRDF's fundamental grade?

Based on our AI fundamental analysis in June 2026, Cardiff Oncology, Inc. has a D grade with 88% confidence. Review the strengths and risks sections above for full context. This is not investment advice.

Is CRDF stock overvalued or undervalued?

Valuation metrics for CRDF: ROE of -35.6% (sector avg: 15%), net margin of -30,109.8% (sector avg: 12%). Compare these metrics with sector averages to assess valuation.

What is CRDF's AI grade for 2026?

Our dual AI analysis gives Cardiff Oncology, Inc. a combined D grade for 2026. Revenue is data pending, with profitability at or below sector average. Always conduct your own research.

What is CRDF's free cash flow?

Cardiff Oncology, Inc.'s operating cash flow is $-12.3M, with capital expenditures of $44.0K. FCF margin is -30,078.0%.

How does CRDF compare to other Healthcare stocks?

Vs Healthcare sector averages: Net margin -30,109.8% (avg: 12%), ROE -35.6% (avg: 15%), current ratio 3.27 (avg: 2).

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Disclaimer: This analysis is generated by Claude AI (Anthropic) and ChatGPT (OpenAI) based on publicly available SEC EDGAR filings. It does not include stock price data and should not be considered financial advice. All fundamental data is sourced from SEC public domain filings. Always conduct your own research and consult with a qualified financial advisor before making investment decisions.
Data Source: SEC EDGAR | Analysis Date: May 16, 2026 | Data as of: 2026-03-31 | Powered by Claude AI