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aTYR PHARMA INC (ATYR) Fundamental Analysis & AI Grade 2026

ATYR Nasdaq Biological Products, (No Diagnostic Substances) DE CIK: 0001339970
Updated This Month • Analysis: May 16, 2026 • SEC Data: 2026-03-31
Combined AI Grade
D
88% Confidence
STRONG AGREEMENT
D
88% Conf
D
87% Conf

📊 ATYR Key Takeaways

Revenue: $190.0K
Net Margin: -5,679.5%
Free Cash Flow: $-12.7M
Current Ratio: 5.78x
Debt/Equity: 0.05x
EPS: $-0.11
AI Grade: D with 88% confidence
aTYR PHARMA INC (ATYR) receives a D fundamental grade with 88% confidence from our AI analysis based on SEC 10-K filings. With revenue of $190.0K, net profit margin of -5,679.5%, and return on equity (ROE) of -18.6%, aTYR PHARMA INC demonstrates mixed fundamentals in the Healthcare sector. Below is our complete ATYR stock analysis for 2026.

Is aTYR PHARMA INC (ATYR) a Good Investment?

Claude

aTYR Pharma faces critical financial distress with revenue of only $190K against $12.5M annual operating cash burn, leaving less than one year of cash runway. The company exhibits the financial profile of an early-stage biotech with zero commercial traction, declining revenue (-19.1% YoY), and structurally unsustainable operations requiring immediate external funding or strategic pivot.

ChatGPT

aTyr Pharma's fundamentals are very weak: revenue is negligible and declining, while operating and net losses remain massive relative to the size of the business. Although leverage is low and current liquidity ratios look strong, the combination of just $10.74M in cash against roughly $62.06M of annual free cash outflow points to significant funding risk and poor growth quality.

aTYR PHARMA INC Key Strengths (ATYR)

Claude
  • + Minimal debt burden with 0.05x debt-to-equity ratio
  • + Positive stockholders' equity of $57.9M provides balance sheet foundation
  • + Strong current ratio of 5.78x indicates technical liquidity despite operational distress
ChatGPT
  • + Low balance-sheet leverage with debt/equity of 0.04x
  • + Current and quick ratios of 5.30x indicate limited near-term liability pressure
  • + Positive YoY EPS improvement suggests some cost discipline at the per-share level

ATYR Stock Risks: aTYR PHARMA INC Investment Risks

Claude
  • ! Critical cash runway of approximately 10 months at current $12.5M annual burn rate with only $10M liquid reserves
  • ! Negligible revenue of $190K against massive operating losses of $11.4M indicates zero commercial viability
  • ! Declining year-over-year revenue trend (-19.1%) suggests deteriorating business momentum without offsetting cost reduction
ChatGPT
  • ! Revenue base is extremely small at $190K and declined 19.1% YoY
  • ! Profitability is deeply negative with net loss of $74.12M and net margin around -39009.5%
  • ! Cash burn is severe, with operating cash flow of -$61.99M versus only $10.74M of cash on hand

Key Metrics to Watch

Claude
  • * Cash position and runway - critical threshold for survival
  • * Operating cash burn rate - trend toward sustainability or accelerating deterioration
  • * Revenue inflection - any meaningful commercial progress or clinical milestone funding
ChatGPT
  • * Quarterly operating cash burn relative to cash and equivalents
  • * Clinical/commercial revenue traction and any sustained reduction in operating loss

aTYR PHARMA INC (ATYR) Financial Metrics & Key Ratios

Revenue
$190.0K
Net Income
$-10.8M
EPS (Diluted)
$-0.11
Free Cash Flow
$-12.7M
Total Assets
$79.7M
Cash Position
$10.0M

💡 AI Analyst Insight

Strong liquidity with a 5.78x current ratio provides a solid financial cushion.

ATYR Profit Margin, ROE & Profitability Analysis

Gross Margin N/A
Operating Margin -6,018.9%
Net Margin -5,679.5%
ROE -18.6%
ROA -13.5%
FCF Margin -6,660.5%

ATYR vs Healthcare Sector: How aTYR PHARMA INC Compares

How aTYR PHARMA INC compares to Healthcare sector averages

Net Margin
ATYR -5,679.5%
vs
Sector Avg 12.0%
ATYR Sector
ROE
ATYR -18.6%
vs
Sector Avg 15.0%
ATYR Sector
Current Ratio
ATYR 5.8x
vs
Sector Avg 2.0x
ATYR Sector
Debt/Equity
ATYR 0.0x
vs
Sector Avg 0.6x
ATYR Sector

Sector benchmarks are approximate industry averages. Actual sector performance may vary.

Is aTYR PHARMA INC Stock Overvalued? ATYR Valuation Analysis 2026

Based on fundamental analysis, aTYR PHARMA INC has mixed fundamental signals relative to the Healthcare sector in 2026.

Return on Equity
-18.6%
Sector avg: 15%
Net Profit Margin
-5,679.5%
Sector avg: 12%
Revenue Growth
N/A
Year-over-year
Debt/Equity
0.05x
Sector avg: 0.6x

Note: This is a fundamental analysis based on SEC filings. For P/E ratio, price targets, and market-based valuation, consult financial data providers. This is not investment advice.

aTYR PHARMA INC Balance Sheet: ATYR Debt, Cash & Liquidity

Current Ratio
5.78x
Quick Ratio
5.78x
Debt/Equity
0.05x
Debt/Assets
0.0%
Interest Coverage
N/A
Long-term Debt
$2.7M

ATYR Revenue & Earnings Growth: 5-Year Financial Trend

ATYR 5-year financial data: Year 2021: Revenue $10.5M, Net Income -$23.6M, EPS N/A. Year 2022: Revenue $10.5M, Net Income -$16.2M, EPS $-1.77. Year 2023: Revenue $10.4M, Net Income -$33.8M, EPS $-1.77. Year 2024: Revenue $10.4M, Net Income -$45.3M, EPS $-1.60. Year 2025: Revenue $353.0K, Net Income -$50.4M, EPS $-0.94.
Revenue
Net Income
EPS (right axis)

5-Year Trend Summary: aTYR PHARMA INC's revenue has declined by 97% over the 5-year period, indicating business contraction. The most recent EPS of $-0.94 indicates the company is currently unprofitable.

ATYR Revenue Growth, EPS Growth & YoY Performance

Revenue Growth
N/A
Year-over-year
Net Income Growth
N/A
Year-over-year
EPS Growth
N/A
Earnings per share
FCF Margin
-6,660.5%
Free cash flow / Revenue

ATYR Quarterly Earnings & Performance

Quarterly financial performance data for aTYR PHARMA INC including revenue, net income, and earnings per share.
Quarter Revenue Net Income EPS
Q3 2025 N/A -$17.3M $-0.23
Q2 2025 N/A -$16.3M $-0.22
Q1 2025 N/A -$14.9M $-0.17
Q3 2024 N/A -$11.3M $-0.20
Q2 2024 N/A -$12.3M $-0.22
Q1 2024 N/A -$12.0M $-0.23
Q3 2023 N/A -$11.3M $-0.20
Q3 2021 $148.0K -$6.6M N/A

Data sourced from SEC EDGAR 10-Q quarterly filings. Figures may represent quarterly or cumulative values.

aTYR PHARMA INC Dividends, Buybacks & Capital Allocation

Operating Cash Flow
-$12.5M
Cash generated from operations
Capital Expenditures
$138.0K
Investment in assets
Dividends
None
No dividend program

ATYR SEC Filings: Latest 10-K & 10-Q Analysis

Access official SEC EDGAR filings for aTYR PHARMA INC (CIK: 0001339970)

📋 Recent SEC Filings

Date Form Document Action
Jun 8, 2026 8-K atyr-20260603.htm View →
Jun 1, 2026 8-K atyr-20260601.htm View →
May 28, 2026 4 xslF345X06/ownership.xml View →
May 15, 2026 10-Q atyr-20260331.htm View →
May 15, 2026 8-K atyr-20260515.htm View →

Frequently Asked Questions about ATYR

What is the AI rating for ATYR?

aTYR PHARMA INC (ATYR) has a Combined AI Grade of D from Claude (D) and ChatGPT (D) with 88% combined confidence, based on fundamental analysis of SEC EDGAR filings.

What are ATYR's key strengths?

Claude: Minimal debt burden with 0.05x debt-to-equity ratio. Positive stockholders' equity of $57.9M provides balance sheet foundation. ChatGPT: Low balance-sheet leverage with debt/equity of 0.04x. Current and quick ratios of 5.30x indicate limited near-term liability pressure.

What are the risks of investing in ATYR?

Claude: Critical cash runway of approximately 10 months at current $12.5M annual burn rate with only $10M liquid reserves. Negligible revenue of $190K against massive operating losses of $11.4M indicates zero commercial viability. ChatGPT: Revenue base is extremely small at $190K and declined 19.1% YoY. Profitability is deeply negative with net loss of $74.12M and net margin around -39009.5%.

What is ATYR's revenue and growth?

aTYR PHARMA INC reported revenue of $190.0K.

Does ATYR pay dividends?

aTYR PHARMA INC does not currently pay dividends.

Where can I find ATYR SEC filings?

Official SEC filings for aTYR PHARMA INC (CIK: 0001339970) including 10-K, 10-Q, and 8-K reports are available on SEC EDGAR.

What is ATYR's EPS?

aTYR PHARMA INC has a diluted EPS of $-0.11.

How is the AI analysis conducted?

Two independent AI systems — Claude (Anthropic) and ChatGPT (OpenAI) — analyze SEC EDGAR filings including 10-K annual reports and 10-Q quarterly reports. Each AI evaluates financial health, profitability ratios, balance sheet strength, and growth metrics. The combined grade reflects both perspectives for balanced insights.

What is ATYR's fundamental grade?

Based on our AI fundamental analysis in June 2026, aTYR PHARMA INC has a D grade with 88% confidence. Review the strengths and risks sections above for full context. This is not investment advice.

Is ATYR stock overvalued or undervalued?

Valuation metrics for ATYR: ROE of -18.6% (sector avg: 15%), net margin of -5,679.5% (sector avg: 12%). Compare these metrics with sector averages to assess valuation.

What is ATYR's AI grade for 2026?

Our dual AI analysis gives aTYR PHARMA INC a combined D grade for 2026. Revenue is data pending, with profitability at or below sector average. Always conduct your own research.

What is ATYR's free cash flow?

aTYR PHARMA INC's operating cash flow is $-12.5M, with capital expenditures of $138.0K. FCF margin is -6,660.5%.

How does ATYR compare to other Healthcare stocks?

Vs Healthcare sector averages: Net margin -5,679.5% (avg: 12%), ROE -18.6% (avg: 15%), current ratio 5.78 (avg: 2).

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Disclaimer: This analysis is generated by Claude AI (Anthropic) and ChatGPT (OpenAI) based on publicly available SEC EDGAR filings. It does not include stock price data and should not be considered financial advice. All fundamental data is sourced from SEC public domain filings. Always conduct your own research and consult with a qualified financial advisor before making investment decisions.
Data Source: SEC EDGAR | Analysis Date: May 16, 2026 | Data as of: 2026-03-31 | Powered by Claude AI