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Kezar Life Sciences, Inc. (KZR) Fundamental Analysis & AI Grade 2026

KZR Nasdaq Pharmaceutical Preparations DE CIK: 0001645666
Updated This Month • Analysis: May 14, 2026 • SEC Data: 2026-03-31
Combined AI Grade
C
55% Confidence
AGREEMENT
B
38% Conf
C
72% Conf

📊 KZR Key Takeaways

Revenue: $0.0
Net Margin: N/A
Free Cash Flow: $-7.4M
Current Ratio: 24.46x
Debt/Equity: 0.00x
EPS: $-0.78
AI Grade: B with 38% confidence
Kezar Life Sciences, Inc. (KZR) receives a C fundamental grade with 55% confidence from our AI analysis based on SEC 10-K filings. With revenue of $0, and return on equity (ROE) of -8.8%, Kezar Life Sciences, Inc. demonstrates mixed fundamentals in the Healthcare sector. Below is our complete KZR stock analysis for 2026.

Is Kezar Life Sciences, Inc. (KZR) a Good Investment?

Claude

Kezar Life Sciences exhibits exceptional financial stability with $66.2M in cash, zero debt, and a 9+ year cash runway, but remains pre-revenue with negative operating cash flow of -$7.4M. While improving net losses year-over-year suggest operational efficiency gains, the company lacks commercial traction and depends entirely on clinical/regulatory milestones not visible in financial data. Rating reflects strong balance sheet fundamentals offset by existential pre-revenue operational risk.

ChatGPT

Kezar is a pre-revenue biotech with sustained operating losses and negative free cash flow, offset by a sizable cash balance and no debt. At the current burn (~$52M OCF) versus ~$72M cash, liquidity covers roughly 12–18 months before likely external financing is needed. Despite YoY loss improvement, fundamentals show no near-term path to profitability or revenue.

Kezar Life Sciences, Inc. Key Strengths (KZR)

Claude
  • + Exceptional cash position ($66.2M) representing 97% of total assets with zero long-term debt, providing 8-9 year runway at current burn rates
  • + No leverage or refinancing risk with current ratio of 24.46x and debt-to-equity of 0.00x
  • + Improving loss trajectory with 33% YoY improvement in net income indicating better operational efficiency
ChatGPT
  • + Strong liquidity with 11.5x current ratio and ~$72M cash
  • + Debt-free balance sheet; minimal fixed obligations
  • + YoY improvement in net loss and negligible capex

KZR Stock Risks: Kezar Life Sciences, Inc. Investment Risks

Claude
  • ! Pre-commercial stage with zero revenue generation; company entirely dependent on cash reserves without revenue traction
  • ! Persistent negative operating cash flow of -$7.4M per period with no clear profitability pathway visible in financials
  • ! Clinical-stage pharmaceutical development carries high regulatory failure risk and likely requires future capital raises causing shareholder dilution
ChatGPT
  • ! No revenue and persistent large operating losses
  • ! Cash runway likely under two years, implying financing/dilution risk
  • ! Negative ROE/ROA and interest coverage reflect weak profitability trajectory

Key Metrics to Watch

Claude
  • * Operating cash burn rate and changes to quarterly cash flow burn trajectory
  • * Absolute cash position and calculated runway extension as key survival metric
  • * Clinical trial advancement, regulatory filings, and potential revenue inception timeline
ChatGPT
  • * Operating cash flow (burn rate)
  • * Cash & equivalents (runway)

Kezar Life Sciences, Inc. (KZR) Financial Metrics & Key Ratios

Revenue
$0.0
Net Income
$-5.8M
EPS (Diluted)
$-0.78
Free Cash Flow
$-7.4M
Total Assets
$68.0M
Cash Position
$66.2M

💡 AI Analyst Insight

Strong liquidity with a 24.46x current ratio provides a solid financial cushion.

KZR Profit Margin, ROE & Profitability Analysis

Gross Margin N/A
Operating Margin N/A
Net Margin N/A
ROE -8.8%
ROA -8.5%
FCF Margin N/A

KZR vs Healthcare Sector: How Kezar Life Sciences, Inc. Compares

How Kezar Life Sciences, Inc. compares to Healthcare sector averages

Net Margin
KZR 0.0%
vs
Sector Avg 12.0%
KZR Sector
ROE
KZR -8.8%
vs
Sector Avg 15.0%
KZR Sector
Current Ratio
KZR 24.5x
vs
Sector Avg 2.0x
KZR Sector
Debt/Equity
KZR 0.0x
vs
Sector Avg 0.6x
KZR Sector

Sector benchmarks are approximate industry averages. Actual sector performance may vary.

Is Kezar Life Sciences, Inc. Stock Overvalued? KZR Valuation Analysis 2026

Based on fundamental analysis, Kezar Life Sciences, Inc. has mixed fundamental signals relative to the Healthcare sector in 2026.

Return on Equity
-8.8%
Sector avg: 15%
Net Profit Margin
N/A
Sector avg: 12%
Revenue Growth
N/A
Year-over-year
Debt/Equity
0.00x
Sector avg: 0.6x

Note: This is a fundamental analysis based on SEC filings. For P/E ratio, price targets, and market-based valuation, consult financial data providers. This is not investment advice.

Kezar Life Sciences, Inc. Balance Sheet: KZR Debt, Cash & Liquidity

Current Ratio
24.46x
Quick Ratio
24.46x
Debt/Equity
0.00x
Debt/Assets
4.1%
Interest Coverage
-6.12x
Long-term Debt
$0.0

KZR Revenue & Earnings Growth: 5-Year Financial Trend

KZR 5-year financial data: Year 2023: Revenue $7.0M, Net Income -$54.6M, EPS $-1.04. Year 2024: Revenue $7.0M, Net Income -$68.2M, EPS $-10.13. Year 2025: Revenue $7.0M, Net Income -$101.9M, EPS $-14.04.
Revenue
Net Income
EPS (right axis)

5-Year Trend Summary: Kezar Life Sciences, Inc.'s revenue has remained relatively flat over the 5-year period, with a 0% decline. The most recent EPS of $-14.04 indicates the company is currently unprofitable.

KZR Revenue Growth, EPS Growth & YoY Performance

Revenue Growth
N/A
Year-over-year
Net Income Growth
N/A
Year-over-year
EPS Growth
N/A
Earnings per share
FCF Margin
N/A
Free cash flow / Revenue

KZR Quarterly Earnings & Performance

Quarterly financial performance data for Kezar Life Sciences, Inc. including revenue, net income, and earnings per share.
Quarter Revenue Net Income EPS
Q3 2024 N/A -$20.3M $-2.78
Q3 2023 N/A -$16.0M $-0.25

Data sourced from SEC EDGAR 10-Q quarterly filings. Figures may represent quarterly or cumulative values.

Kezar Life Sciences, Inc. Dividends, Buybacks & Capital Allocation

Operating Cash Flow
-$7.4M
Cash generated from operations
Dividends
None
No dividend program

KZR SEC Filings: Latest 10-K & 10-Q Analysis

Access official SEC EDGAR filings for Kezar Life Sciences, Inc. (CIK: 0001645666)

📋 Recent SEC Filings

Date Form Document Action
May 11, 2026 4 xslF345X06/form4-05112026_040521.xml View →
May 11, 2026 4 xslF345X06/form4-05112026_040519.xml View →
May 11, 2026 4 xslF345X06/form4-05112026_040517.xml View →
May 11, 2026 4 xslF345X06/form4-05112026_040515.xml View →
May 11, 2026 4 xslF345X06/form4-05112026_040513.xml View →

Frequently Asked Questions about KZR

What is the AI rating for KZR?

Kezar Life Sciences, Inc. (KZR) has a Combined AI Grade of C from Claude (B) and ChatGPT (C) with 55% combined confidence, based on fundamental analysis of SEC EDGAR filings.

What are KZR's key strengths?

Claude: Exceptional cash position ($66.2M) representing 97% of total assets with zero long-term debt, providing 8-9 year runway at current burn rates. No leverage or refinancing risk with current ratio of 24.46x and debt-to-equity of 0.00x. ChatGPT: Strong liquidity with 11.5x current ratio and ~$72M cash. Debt-free balance sheet; minimal fixed obligations.

What are the risks of investing in KZR?

Claude: Pre-commercial stage with zero revenue generation; company entirely dependent on cash reserves without revenue traction. Persistent negative operating cash flow of -$7.4M per period with no clear profitability pathway visible in financials. ChatGPT: No revenue and persistent large operating losses. Cash runway likely under two years, implying financing/dilution risk.

What is KZR's revenue and growth?

Kezar Life Sciences, Inc. reported revenue of $0.0.

Does KZR pay dividends?

Kezar Life Sciences, Inc. does not currently pay dividends.

Where can I find KZR SEC filings?

Official SEC filings for Kezar Life Sciences, Inc. (CIK: 0001645666) including 10-K, 10-Q, and 8-K reports are available on SEC EDGAR.

What is KZR's EPS?

Kezar Life Sciences, Inc. has a diluted EPS of $-0.78.

How is the AI analysis conducted?

Two independent AI systems — Claude (Anthropic) and ChatGPT (OpenAI) — analyze SEC EDGAR filings including 10-K annual reports and 10-Q quarterly reports. Each AI evaluates financial health, profitability ratios, balance sheet strength, and growth metrics. The combined grade reflects both perspectives for balanced insights.

What is KZR's fundamental grade?

Based on our AI fundamental analysis in June 2026, Kezar Life Sciences, Inc. has a C grade with 55% confidence. Review the strengths and risks sections above for full context. This is not investment advice.

Is KZR stock overvalued or undervalued?

Valuation metrics for KZR: ROE of -8.8% (sector avg: 15%), net margin of N/A (sector avg: 12%). Compare these metrics with sector averages to assess valuation.

What is KZR's AI grade for 2026?

Our dual AI analysis gives Kezar Life Sciences, Inc. a combined C grade for 2026. Revenue is data pending, with profitability at or below sector average. Always conduct your own research.

What is KZR's free cash flow?

Kezar Life Sciences, Inc.'s operating cash flow is $-7.4M, with capital expenditures of $0.0.

How does KZR compare to other Healthcare stocks?

Vs Healthcare sector averages: Net margin N/A (avg: 12%), ROE -8.8% (avg: 15%), current ratio 24.46 (avg: 2).

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Disclaimer: This analysis is generated by Claude AI (Anthropic) and ChatGPT (OpenAI) based on publicly available SEC EDGAR filings. It does not include stock price data and should not be considered financial advice. All fundamental data is sourced from SEC public domain filings. Always conduct your own research and consult with a qualified financial advisor before making investment decisions.
Data Source: SEC EDGAR | Analysis Date: May 14, 2026 | Data as of: 2026-03-31 | Powered by Claude AI