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Palisade Bio, Inc.. (PALI) Fundamental Analysis & AI Grade 2026

PALI Nasdaq Biological Products, (No Diagnostic Substances) DE CIK: 0001357459
Updated This Month • Analysis: May 13, 2026 • SEC Data: 2026-03-31
Combined AI Grade
B
55% Confidence
N/A
B
55% Conf
Pending
Analysis scheduled

📊 PALI Key Takeaways

Revenue: $0.0
Net Margin: N/A
Free Cash Flow: $-3.9M
Current Ratio: 23.71x
Debt/Equity: 0.00x
EPS: $-0.05
AI Grade: B with 55% confidence
Palisade Bio, Inc.. (PALI) receives a B fundamental grade with 55% confidence from our AI analysis based on SEC 10-K filings. With revenue of $0, and return on equity (ROE) of -7.5%, Palisade Bio, Inc.. demonstrates mixed fundamentals in the Healthcare sector. Below is our complete PALI stock analysis for 2026.

Is Palisade Bio, Inc.. (PALI) a Good Investment?

Claude

Palisade Bio is a pre-revenue biotech with exceptionally strong financial health: $132.6M cash, minimal debt, and a 34+ year cash runway at current burn rates. However, zero revenue and lack of visible commercialization pathway limit upside assessment; the 97.1% YoY improvement in EPS losses suggests operational discipline, but fundamental progress remains elusive.

Palisade Bio, Inc.. Key Strengths (PALI)

Claude
  • + Exceptional liquidity position with $132.6M cash (99.5% of total assets) and 23.71x current ratio
  • + Minimal debt burden ($87K long-term) and fortress balance sheet with $127.4M stockholders' equity
  • + Significant 97.1% YoY improvement in diluted EPS losses, indicating operational efficiency gains

PALI Stock Risks: Palisade Bio, Inc.. Investment Risks

Claude
  • ! Zero revenue with no evidence of commercial product viability or market acceptance
  • ! Negative operating cash flow of $3.9M annually indicates persistent capital burn without offsetting revenue
  • ! Pre-revenue biotech status with unclear clinical pipeline, regulatory approval timeline, and path to profitability

Key Metrics to Watch

Claude
  • * Revenue generation timeline and first commercial product launch milestones
  • * Operating cash burn rate trajectory and remaining cash runway sustainability
  • * Clinical development pipeline progression and regulatory approval status

Palisade Bio, Inc.. (PALI) Financial Metrics & Key Ratios

Revenue
$0.0
Net Income
$-9.6M
EPS (Diluted)
$-0.05
Free Cash Flow
$-3.9M
Total Assets
$133.3M
Cash Position
$132.6M

💡 AI Analyst Insight

Strong liquidity with a 23.71x current ratio provides a solid financial cushion.

PALI Profit Margin, ROE & Profitability Analysis

Gross Margin N/A
Operating Margin N/A
Net Margin N/A
ROE -7.5%
ROA -7.2%
FCF Margin N/A

PALI vs Healthcare Sector: How Palisade Bio, Inc.. Compares

How Palisade Bio, Inc.. compares to Healthcare sector averages

Net Margin
PALI 0.0%
vs
Sector Avg 12.0%
PALI Sector
ROE
PALI -7.5%
vs
Sector Avg 15.0%
PALI Sector
Current Ratio
PALI 23.7x
vs
Sector Avg 2.0x
PALI Sector
Debt/Equity
PALI 0.0x
vs
Sector Avg 0.6x
PALI Sector

Sector benchmarks are approximate industry averages. Actual sector performance may vary.

Is Palisade Bio, Inc.. Stock Overvalued? PALI Valuation Analysis 2026

Based on fundamental analysis, Palisade Bio, Inc.. has mixed fundamental signals relative to the Healthcare sector in 2026.

Return on Equity
-7.5%
Sector avg: 15%
Net Profit Margin
N/A
Sector avg: 12%
Revenue Growth
N/A
Year-over-year
Debt/Equity
0.00x
Sector avg: 0.6x

Note: This is a fundamental analysis based on SEC filings. For P/E ratio, price targets, and market-based valuation, consult financial data providers. This is not investment advice.

Palisade Bio, Inc.. Balance Sheet: PALI Debt, Cash & Liquidity

Current Ratio
23.71x
Quick Ratio
23.71x
Debt/Equity
0.00x
Debt/Assets
4.5%
Interest Coverage
-1,343.50x
Long-term Debt
$87.0K

PALI Revenue & Earnings Growth: 5-Year Financial Trend

PALI 5-year financial data: Year 2023: Revenue $250.0K, Net Income -$14.3M, EPS $-16.53. Year 2024: Revenue $250.0K, Net Income -$12.3M, EPS $-27.01.
Revenue
Net Income
EPS (right axis)

5-Year Trend Summary: Palisade Bio, Inc..'s revenue has remained relatively flat over the 5-year period, with a 0% decline. The most recent EPS of $-10.19 indicates the company is currently unprofitable.

PALI Revenue Growth, EPS Growth & YoY Performance

Revenue Growth
N/A
Year-over-year
Net Income Growth
N/A
Year-over-year
EPS Growth
N/A
Earnings per share
FCF Margin
N/A
Free cash flow / Revenue

PALI Quarterly Earnings & Performance

Quarterly financial performance data for Palisade Bio, Inc.. including revenue, net income, and earnings per share.
Quarter Revenue Net Income EPS
Q3 2024 N/A -$3.5M $-2.32
Q2 2024 N/A -$3.4M $-3.32
Q1 2024 N/A -$2.3M $-4.59
Q3 2023 N/A -$3.6M $-0.49
Q2 2023 N/A -$2.3M $-0.53
Q1 2023 N/A -$2.3M $-0.54

Data sourced from SEC EDGAR 10-Q quarterly filings. Figures may represent quarterly or cumulative values.

Palisade Bio, Inc.. Dividends, Buybacks & Capital Allocation

Operating Cash Flow
-$3.9M
Cash generated from operations
Dividends
None
No dividend program

PALI SEC Filings: Latest 10-K & 10-Q Analysis

Access official SEC EDGAR filings for Palisade Bio, Inc.. (CIK: 0001357459)

📋 Recent SEC Filings

Date Form Document Action
May 12, 2026 8-K pali-20260512.htm View →
May 12, 2026 10-Q pali-20260331.htm View →
Apr 29, 2026 DEF 14A formdef14a.htm View →
Apr 2, 2026 8-K form8-k.htm View →
Mar 20, 2026 10-K pali-20251231.htm View →

Frequently Asked Questions about PALI

What is the AI rating for PALI?

Palisade Bio, Inc.. (PALI) has an AI grade of B with 55% confidence, based on fundamental analysis of SEC EDGAR filings.

What are PALI's key strengths?

Claude: Exceptional liquidity position with $132.6M cash (99.5% of total assets) and 23.71x current ratio. Minimal debt burden ($87K long-term) and fortress balance sheet with $127.4M stockholders' equity.

What are the risks of investing in PALI?

Claude: Zero revenue with no evidence of commercial product viability or market acceptance. Negative operating cash flow of $3.9M annually indicates persistent capital burn without offsetting revenue.

What is PALI's revenue and growth?

Palisade Bio, Inc.. reported revenue of $0.0.

Does PALI pay dividends?

Palisade Bio, Inc.. does not currently pay dividends.

Where can I find PALI SEC filings?

Official SEC filings for Palisade Bio, Inc.. (CIK: 0001357459) including 10-K, 10-Q, and 8-K reports are available on SEC EDGAR.

What is PALI's EPS?

Palisade Bio, Inc.. has a diluted EPS of $-0.05.

How is the AI analysis conducted?

Two independent AI systems — Claude (Anthropic) and ChatGPT (OpenAI) — analyze SEC EDGAR filings including 10-K annual reports and 10-Q quarterly reports. Each AI evaluates financial health, profitability ratios, balance sheet strength, and growth metrics. The combined grade reflects both perspectives for balanced insights.

What is PALI's fundamental grade?

Based on our AI fundamental analysis in June 2026, Palisade Bio, Inc.. has a B grade with 55% confidence. Review the strengths and risks sections above for full context. This is not investment advice.

Is PALI stock overvalued or undervalued?

Valuation metrics for PALI: ROE of -7.5% (sector avg: 15%), net margin of N/A (sector avg: 12%). Compare these metrics with sector averages to assess valuation.

What is PALI's AI grade for 2026?

Our dual AI analysis gives Palisade Bio, Inc.. a combined B grade for 2026. Revenue is data pending, with profitability at or below sector average. Always conduct your own research.

What is PALI's free cash flow?

Palisade Bio, Inc..'s operating cash flow is $-3.9M, with capital expenditures of $0.0.

How does PALI compare to other Healthcare stocks?

Vs Healthcare sector averages: Net margin N/A (avg: 12%), ROE -7.5% (avg: 15%), current ratio 23.71 (avg: 2).

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Disclaimer: This analysis is generated by Claude AI (Anthropic) and ChatGPT (OpenAI) based on publicly available SEC EDGAR filings. It does not include stock price data and should not be considered financial advice. All fundamental data is sourced from SEC public domain filings. Always conduct your own research and consult with a qualified financial advisor before making investment decisions.
Data Source: SEC EDGAR | Analysis Date: May 13, 2026 | Data as of: 2026-03-31 | Powered by Claude AI