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Skye Bioscience, Inc. (SKYE) Fundamental Analysis & AI Grade 2026

SKYE Nasdaq Pharmaceutical Preparations NV CIK: 0001516551
Updated This Month • Analysis: May 16, 2026 • SEC Data: 2026-03-31
Combined AI Grade
D
92% Confidence
N/A
D
92% Conf
Pending
Analysis scheduled

📊 SKYE Key Takeaways

Revenue: N/A
Net Margin: N/A
Free Cash Flow: $-8.6M
Current Ratio: 1.78x
Debt/Equity: 0.01x
EPS: $-0.32
AI Grade: D with 92% confidence
Skye Bioscience, Inc. (SKYE) receives a D fundamental grade with 92% confidence from our AI analysis based on SEC 10-K filings., and return on equity (ROE) of -138.8% Below is our complete SKYE stock analysis for 2026.

Is Skye Bioscience, Inc. (SKYE) a Good Investment?

Claude

Skye Bioscience exhibits severe financial distress with no revenue generation, cumulative losses of $12.5M, and negative operating cash flow of $8.6M annually, leaving approximately 11 months of cash runway at current burn rate. The company's deteriorating profitability (-93.2% EPS decline YoY), negative returns (ROE -138.8%, ROA -64.4%), and apparent failure to commercialize its pharmaceutical pipeline present fundamental business viability concerns that cannot be offset by its modest liquidity position.

Skye Bioscience, Inc. Key Strengths (SKYE)

Claude
  • + Strong liquidity with 1.78x current ratio, providing short-term operational flexibility
  • + Minimal leverage with 0.01x debt-to-equity ratio, reducing bankruptcy risk from debt default
  • + Modest asset base of $19.4M provides some liquidation value cushion

SKYE Stock Risks: Skye Bioscience, Inc. Investment Risks

Claude
  • ! Zero or negligible revenue indicates failed commercialization or pre-revenue stage with no near-term monetization
  • ! Annual operating cash burn of $8.6M against $8.1M cash reserves provides less than 12 months of runway at current burn rate
  • ! Negative returns on capital (-138.8% ROE, -64.4% ROA) demonstrate complete destruction of shareholder value
  • ! Deteriorating EPS (-93.2% YoY) indicates worsening operational performance with no recovery trajectory visible
  • ! Pharmaceutical sector execution risk: clinical failure, regulatory rejection, or competitive displacement of pipeline

Key Metrics to Watch

Claude
  • * Operating cash burn rate and remaining cash runway (critical near-term survival metric)
  • * Revenue generation (any emergence of commercial revenue would dramatically alter thesis)
  • * Operating loss trend and path to cash flow breakeven
  • * Clinical trial results and regulatory milestones for pharmaceutical pipeline

Skye Bioscience, Inc. (SKYE) Financial Metrics & Key Ratios

Revenue
N/A
Net Income
$-12.5M
EPS (Diluted)
$-0.32
Free Cash Flow
$-8.6M
Total Assets
$19.4M
Cash Position
$8.1M

💡 AI Analyst Insight

Skye Bioscience, Inc. presents a mixed fundamental picture. Review the detailed metrics above to form your own investment thesis.

SKYE Profit Margin, ROE & Profitability Analysis

Gross Margin N/A
Operating Margin N/A
Net Margin N/A
ROE -138.8%
ROA -64.4%
FCF Margin N/A

SKYE vs Healthcare Sector: How Skye Bioscience, Inc. Compares

How Skye Bioscience, Inc. compares to Healthcare sector averages

Net Margin
SKYE 0.0%
vs
Sector Avg 12.0%
SKYE Sector
ROE
SKYE -138.8%
vs
Sector Avg 15.0%
SKYE Sector
Current Ratio
SKYE 1.8x
vs
Sector Avg 2.0x
SKYE Sector
Debt/Equity
SKYE 0.0x
vs
Sector Avg 0.6x
SKYE Sector

Sector benchmarks are approximate industry averages. Actual sector performance may vary.

Is Skye Bioscience, Inc. Stock Overvalued? SKYE Valuation Analysis 2026

Based on fundamental analysis, Skye Bioscience, Inc. has mixed fundamental signals relative to the Healthcare sector in 2026.

Return on Equity
-138.8%
Sector avg: 15%
Net Profit Margin
N/A
Sector avg: 12%
Revenue Growth
N/A
Year-over-year
Debt/Equity
0.01x
Sector avg: 0.6x

Note: This is a fundamental analysis based on SEC filings. For P/E ratio, price targets, and market-based valuation, consult financial data providers. This is not investment advice.

Skye Bioscience, Inc. Balance Sheet: SKYE Debt, Cash & Liquidity

Current Ratio
1.78x
Quick Ratio
1.78x
Debt/Equity
0.01x
Debt/Assets
53.6%
Interest Coverage
N/A
Long-term Debt
$45.6K

SKYE Revenue & Earnings Growth: 5-Year Financial Trend

SKYE 5-year financial data:
Revenue
Net Income
EPS (right axis)

5-Year Trend Summary: Skye Bioscience, Inc.'s revenue has remained relatively flat over the 5-year period, with a 0% decline. The most recent EPS of $-0.73 indicates the company is currently unprofitable.

SKYE Revenue Growth, EPS Growth & YoY Performance

Revenue Growth
N/A
Year-over-year
Net Income Growth
N/A
Year-over-year
EPS Growth
N/A
Earnings per share
FCF Margin
N/A
Free cash flow / Revenue

Skye Bioscience, Inc. Dividends, Buybacks & Capital Allocation

Operating Cash Flow
-$8.6M
Cash generated from operations
Dividends
None
No dividend program

SKYE SEC Filings: Latest 10-K & 10-Q Analysis

Access official SEC EDGAR filings for Skye Bioscience, Inc. (CIK: 0001516551)

📋 Recent SEC Filings

Date Form Document Action
May 29, 2026 8-K skye-20260526.htm View →
May 15, 2026 8-K skye-20260513.htm View →
May 11, 2026 10-Q skye-20260331.htm View →
Apr 16, 2026 DEF 14A skye-20260415.htm View →
Apr 3, 2026 8-K skye-20260331.htm View →

Frequently Asked Questions about SKYE

What is the AI rating for SKYE?

Skye Bioscience, Inc. (SKYE) has an AI grade of D with 92% confidence, based on fundamental analysis of SEC EDGAR filings.

What are SKYE's key strengths?

Claude: Strong liquidity with 1.78x current ratio, providing short-term operational flexibility. Minimal leverage with 0.01x debt-to-equity ratio, reducing bankruptcy risk from debt default.

What are the risks of investing in SKYE?

Claude: Zero or negligible revenue indicates failed commercialization or pre-revenue stage with no near-term monetization. Annual operating cash burn of $8.6M against $8.1M cash reserves provides less than 12 months of runway at current burn rate.

What is SKYE's revenue and growth?

Skye Bioscience, Inc. reported revenue of N/A.

Does SKYE pay dividends?

Skye Bioscience, Inc. does not currently pay dividends.

Where can I find SKYE SEC filings?

Official SEC filings for Skye Bioscience, Inc. (CIK: 0001516551) including 10-K, 10-Q, and 8-K reports are available on SEC EDGAR.

What is SKYE's EPS?

Skye Bioscience, Inc. has a diluted EPS of $-0.32.

How is the AI analysis conducted?

Two independent AI systems — Claude (Anthropic) and ChatGPT (OpenAI) — analyze SEC EDGAR filings including 10-K annual reports and 10-Q quarterly reports. Each AI evaluates financial health, profitability ratios, balance sheet strength, and growth metrics. The combined grade reflects both perspectives for balanced insights.

What is SKYE's fundamental grade?

Based on our AI fundamental analysis in June 2026, Skye Bioscience, Inc. has a D grade with 92% confidence. Review the strengths and risks sections above for full context. This is not investment advice.

Is SKYE stock overvalued or undervalued?

Valuation metrics for SKYE: ROE of -138.8% (sector avg: 15%), net margin of N/A (sector avg: 12%). Compare these metrics with sector averages to assess valuation.

What is SKYE's AI grade for 2026?

Our dual AI analysis gives Skye Bioscience, Inc. a combined D grade for 2026. Revenue is data pending, with profitability at or below sector average. Always conduct your own research.

What is SKYE's free cash flow?

Skye Bioscience, Inc.'s operating cash flow is $-8.6M, with capital expenditures of $0.0.

How does SKYE compare to other Healthcare stocks?

Vs Healthcare sector averages: Net margin N/A (avg: 12%), ROE -138.8% (avg: 15%), current ratio 1.78 (avg: 2).

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Disclaimer: This analysis is generated by Claude AI (Anthropic) and ChatGPT (OpenAI) based on publicly available SEC EDGAR filings. It does not include stock price data and should not be considered financial advice. All fundamental data is sourced from SEC public domain filings. Always conduct your own research and consult with a qualified financial advisor before making investment decisions.
Data Source: SEC EDGAR | Analysis Date: May 16, 2026 | Data as of: 2026-03-31 | Powered by Claude AI